Senior Clinical Lecturer in Gene Therapy

£78,163 - £104,627 per annum
30 Mar 2017
24 Apr 2017
Career Level
Contract Type
Full Time

UCL Great Ormond Street Institute of Child Health

The appointment will be full time on UCL Grade Clinical Senior Lecturer (Consultant). The salary range will be £78,163 - £104,627 per annum, inclusive of London Allowance.

Improving outcomes for children is a major priority in the United Kingdom and has received a major boost with a new strategic initiative between the Great Ormond Street Hospital for Children NHS Foundation Trust (GOSH), UCL’s Great Ormond Street Institute of Child Health (GOS ICH), the Child Health Incorporated Organisation Charity and the Great Ormond Street Hospital Children’s Charity (GOSHCC). These organisations have come together with a commitment to make a strategic investment in Gene Therapy with the establishment of a Clinical Senior Lecturer and three Lecturer positions. These appointments will be part of the excellent clinical and translational research activity at GOSH/GOS ICH which is focused on rare and complex diseases in young children. The generous funding available from the charity together with support of GOSH, ICH and UCL means that we are uniquely positioned to achieve a step-change in the care and treatment of children with rare diseases.

Applications are invited for a Senior Clinical Lecturer to take forward research into gene and cell therapy. Over the last 15 years the gene therapy programme at UCL Institute of Child Health and Great Ormond Street Hospital has grown to become one of the largest programmes worldwide. We have run 7 clinical trials of gene therapy for primary immunodeficiencies, with significant success and with minimal adverse events. The experience and expertise generated has led to the development of other gene and cell therapies for metabolic disease, inherited skin conditions, HIV and T cell therapies for cancer. The programme has attracted international recognition and acclaim for UCL and Great Ormond Street Hospital and is also now attracting significant pharma/commercial interest. There is broad spectrum of expertise ranging from basic vector biology, through proof of concept studies to implementation of clinical trials. Our close relationship with the unique patient population at Great Ormond Street Hospital allows early translation to clinical studies.

We are now looking to enhance our expertise in gene therapy in a variety of different disciplines. We are looking for a highly motivated and capable individual with a strong academic track record, who will take up a faculty position and who is capable of developing their own research group. The individual will be mentored by Professor Thrasher and Professor Gaspar.

Applicants must have Full GMC registration, MRCPCH or equivalent and CST or equivalent in paediatrics. They must have a PhD in a field relevant to gene and cell therapy, an active research profile at postdoctoral level and first/last author original research publications in high quality peer-reviewed scientific journals in a field relevant to gene therapy. They must have clinical training and experience in primary immunodeficiency and BMT.

A job description and person specification can be accessed at the bottom of the page.

For further details about the vacancy and how to apply online please go to  and search on Reference Number:1637259

If you have any queries regarding the vacancy or the application process, please contact Madhur Sharma at  quoting job reference.

Closing date: 24 April 2017

Latest time for the submission of applications:23:59

Interview Date: TBC

Any offer of employment will be subject to a Disclosure and Barring Service (DBS) check.

We particularly welcome female applicants and those from an ethnic minority, as they are under-represented within UCL at this level.

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